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August 2012

Volume 65, Issue 8

cover: In this artist’s representation of a recent experiment on laboratory mice, lipid nanoparticles (white) bombard a cancerous tumor with a cocktail of two drugs (blue and green), one that rallies the body’s immune system against the tumor and one that blocks the tumor’s own defenses against the attack. (J. Park et al., Nature Materials, in press, doi:10.1038/nmat3355.) As discussed in the article by Jennifer Grossman and Scott McNeil on page 38, cancer-fighting nanomaterials have also shown potential in treating human patients. (Image courtesy of Nicolle Rager Fuller, National Science Foundation.)

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Strange kinetics of single molecules in living cells

Eli Barkai, Yuval Garini, and Ralf Metzler
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The irreproducibility of time-averaged observables in living cells poses fundamental questions for statistical mechanics and reshapes our views on cell biology.
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Nanotechnology in cancer medicine

Jennifer H. Grossman and Scott E. McNeil
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Because of a previously unexploited weakness in tumor architecture, nanomaterials may offer a way to treat cancer without doing too much damage to healthy tissue. The weakness isn’t really a property of the tumors themselves but of the blood vessels that feed them.

Theoretical challenges in understanding galaxy evolution

Jeremiah P. Ostriker and Thorsten Naab
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The concordance cosmological model provides initial conditions and a reliable framework for simulating the evolution of primordial fluctuations into galaxies. But many unsolved problems remain.
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back to top Authors comment on authorship commentary
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Authors comment on authorship commentary

Hassel Ledbetter
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Mark Brandon
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Maury Goodman
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Donald D. Clayton
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Tomek Kott
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Lance Nizami
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R. Bruce Doak
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Willem Wieme
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Philip J. Wyatt
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back to top Can a scientist knock on heaven’s door?
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Can a scientist knock on heaven’s door?

Keith Schofield
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back to top Putting the Savannah River Site where it belongs
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Putting the Savannah River Site where it belongs

G. Samuel Lightner
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back to top Corrections
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Corrections

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Hidden starburst galaxy pinpointed at high redshift

Ashley G. Smart
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Stars may have been significantly more abundant in the infant universe than optical surveys alone suggest.

Catching a submarine volcano in the act

R. Mark Wilson
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A swarm of earthquakes and a sudden rise in the sea floor herald an imminent eruption.
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A Higgs particle has been spotted

Steven K. Blau
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When a dusty plasma gets dirty

Stephen G. Benka
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A puzzling pair of planets

Bertram M. Schwarzschild
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A new imaging technique for analyzing art

Richard J. Fitzgerald
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Concentration gradients promote antibiotic resistance

Charles Day
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Plutonium-239 yields to nuclear magnetic resonance

Steven K. Blau
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Scientists poke holes in carbon dioxide sequestration

David Kramer
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Recent findings say earthquakes caused by CO2 injection may cause bottled-up greenhouse gas to leak.

Germany differentiates its universities

Toni Feder
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Winners and losers in a bid for money and prestige say the process has helped universities plan for the future. Many also see the heightened competition as good for research.

Costs for polar-orbiting weather satellites climb again

David Kramer
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Delay in launch of spacecraft is expected to cause deteriorated forecasts.

Jobs for physics doctorates

Toni Feder
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Plasma record in China

Toni Feder
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The Infinity Puzzle: Quantum Field Theory and the Hunt for an Orderly Universe

Chad Orzel, Reviewer
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Introduction to Statistical Mechanics; Statistical Mechanics in a Nutshell

Kimani A. Stancil, Reviewer
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Introduction to Experimental Biophysics: Biological Methods for Physical Scientists

Jennifer L. Ross, Reviewer
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Neither Physics nor Chemistry: A History of Quantum Chemistry

Alán Aspuru-Guzik, Reviewer
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New books

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Focus on analytical equipment and diagnostics

Andreas Mandelis
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Massimilla Baldo Ceolin

Luisa Bonolis and Michael Friedlander
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Frederic Holtzberg

David D. Awschalom, Paul M. Horn, and Stephan von Molnár
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Douglas Leon Mills

Aleksandr L. Chernyshev, Alexei A. Maradudin, Steven R. White, and Clare Yu
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Intrinsically disordered proteins

Peter Tompa and Kyou-Hoon Han
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Researchers are discovering an ever-increasing number of proteins that perform key cellular tasks without having the fixed, three-dimensional structure once thought mandatory for a protein to do its job.
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Derecho looming

Richard J. Fitzgerald
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